variable regions meaning

• [Medicine]
  That region of the immunoglobulin (antibody) molecule that varies in its amino acid sequence and composition,confers the antigenic specificity,and is thought to comprise the binding site for the antigen. It is located at the N-terminus of the Fab fragment of the immunoglobulin. It includes hypervariable regions (COMPLEMENTARITY DETERMINING REGIONS) and framework regions.

• Cloning and expression of the variable region genes of the monoclonal antibody against human cd
• Cloning of variable region and signal peptide genes of anti-cd20 monoclonal antibody by rlm-race
• The framework region makes up about 85 % of the variable region.
• The variable region of light is therefore encoded by the rearrangement of VJ segments.
• The high concentrations of these mutations at the variable region also produce high antibody diversity.
• Second, the third finger loop is the most variable region in sequence, length and conformation.
• The variable region of kappa III amyloid proteins may show an increased likelihood of depositing in soft tissue.
• Nkd proteins consist of at least four well-conserved blocks of amino acid sequence interspersed by variable regions.
• The variable region in turn has hyper-variable regions which are unique amino acid sequences in each antibody.
• The variable region in turn has hyper-variable regions which are unique amino acid sequences in each antibody.

• "variable regions" meaning in Chinese: 《英文msh词典》Variable Regions